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Gosuranemab

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Catalog No. T77028Cas No. 1788032-39-2
Alias IPN007, IPN 007, BMS-986168, BIIB092, BIIB 092

Gosuranemab (BIIB092) is a humanised monoclonal antibody targeting N-terminal tau, inhibiting the propagation and aggregation of pathological tau proteins for potential application in Alzheimer's disease.

Gosuranemab

Gosuranemab

😃Good
Purity: 95%
Catalog No. T77028Alias IPN007, IPN 007, BMS-986168, BIIB092, BIIB 092Cas No. 1788032-39-2
Gosuranemab (BIIB092) is a humanised monoclonal antibody targeting N-terminal tau, inhibiting the propagation and aggregation of pathological tau proteins for potential application in Alzheimer's disease.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$290-In Stock
5 mg$755-In Stock
10 mg$1,280-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:97.5% (SDS-PAGE); 95.2% (SEC-HPLC)
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Product Introduction

Bioactivity
Description
Gosuranemab (BIIB092) is a humanised monoclonal antibody targeting N-terminal tau, inhibiting the propagation and aggregation of pathological tau proteins for potential application in Alzheimer's disease.
In vitro
Pre-incubation of Gosuranemab with AD-tau significantly inhibited tau aggregation in mouse primary cortical neurons [2].
In vivo
Gosuranemab reduces tau aggregation in the cerebrospinal fluid of transgenic mice, inhibits microglial activation, and thereby improves their cognitive dysfunction [2].
SynonymsIPN007, IPN 007, BMS-986168, BIIB092, BIIB 092
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetTau
Chemical Properties
Molecular Weight144.93 kDa
Cas No.1788032-39-2
ColorTransparent
AppearanceLiquid
Antibody Information
IsotypeHuman IgG4 kappa
Recommended Isotype Control
Storage & Solubility Information
Storagestore at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature.

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