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Ganciclovir sodium (Cytovene IV sodium) is the sodium salt of Ganciclovir with antiviral activity, especially against cytomegalovirus (CMV) and herpes simplex virus type 1 (HSV-1).
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 mg | $30 | In Stock | |
100 mg | $42 | In Stock | |
500 mg | $76 | In Stock | |
1 g | $94 | In Stock | |
2 g | $136 | In Stock | |
1 mL x 10 mM (in DMSO) | $46 | In Stock |
Description | Ganciclovir sodium (Cytovene IV sodium) is the sodium salt of Ganciclovir with antiviral activity, especially against cytomegalovirus (CMV) and herpes simplex virus type 1 (HSV-1). |
Targets&IC50 | FHV-1:5.2 μM |
In vitro | Ganciclovir showed activity against feline herpesvirus type-1 (FHV-1, IC50 = 5.2 microM)[1]. |
In vivo | In adult rats, the intracochlear diffusion of ganciclovir was shown to achieve the same concentration as in blood. In gestating mice, transplacental diffusion was observed, with a fetal-to-maternal blood ratio of 0.5. In newborn mice, the plasma concentration profile of ganciclovir showed a peak at 2 h followed by a gradual decrease. In adult mice, the concentration peaked at 1 h, but became undetectable by 2 h after injection. Counts of white blood cells, red blood cells and platelets decreased significantly in ganciclovir-treated newborn mice[3]. |
Alias | RS-21592 sodium, Cytovene IV sodium, BW 759 sodium, 2'-Nor-2'-deoxyguanosine sodium |
Molecular Weight | 278.22 |
Formula | C9H13N5NaO4 |
Cas No. | 107910-75-8 |
Smiles | NC(NC1=C2N=CN1COC(CO)CO)=NC2=O.[Na] |
Relative Density. | 1.81g/cm3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
Solubility Information | H2O: 5 mg/mL (17.97 mM), Sonication is recommended. ![]() DMSO: 3.06 mg/mL (10.98 mM), Sonication is recommended. ![]() | ||||||||||||||||||||
In Vivo Formulation | PBS: 5 mg/mL (17.97 mM), Sonication is recommended. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.![]() | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO/H2O
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