Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(Z)-KC02 is an ABHD16A inhibitor which targets the enzyme responsible for producing lysophosphatidylserine (lyso-PS), a lipid involved in regulating immune and neurological functions. This compound is linked to the mitigation of neurological disorders, including retinitis pigmentosa and cataracts (PHARC), by depleting lyso-PS in lymphoblasts from affected individuals. Moreover, (Z)-KC02 diminishes lyso-PS levels and lipopolysaccharide-induced cytokine production in macrophages and influences lyso-PS metabolism in vivo [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 μg | 35 days | $ 110.00 | |
500 μg | 35 days | $ 458.00 | |
1 mg | 35 days | $ 748.00 |
Description | (Z)-KC02 is an ABHD16A inhibitor which targets the enzyme responsible for producing lysophosphatidylserine (lyso-PS), a lipid involved in regulating immune and neurological functions. This compound is linked to the mitigation of neurological disorders, including retinitis pigmentosa and cataracts (PHARC), by depleting lyso-PS in lymphoblasts from affected individuals. Moreover, (Z)-KC02 diminishes lyso-PS levels and lipopolysaccharide-induced cytokine production in macrophages and influences lyso-PS metabolism in vivo [1]. |
In vitro | (Z)-KC02 disrupts ABHD16A in murine macrophages, thereby reducing lyso-PS levels [1]. |
Molecular Weight | 287.35 |
Formula | C17H21NO3 |
CAS No. | 1646795-60-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
(Z)-KC02 1646795-60-9 inhibitor inhibit