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Anti-CD38 Antibody (4G658) is a Rabbit antibody targeting CD38. Anti-CD38 Antibody (4G658) can be used in WB,ELISA,IP.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $268 | 7-10 days |
Description | Anti-CD38 Antibody (4G658) is a Rabbit antibody targeting CD38. Anti-CD38 Antibody (4G658) can be used in WB,ELISA,IP. |
Alias | T10, CD38 molecule, ADPRC1, ADPRC 1 |
Ig Type | Monoclonal Rabbit IgG |
Clone | 4G658 |
Reactivity | Human |
Verified Activity | 1. Anti-CD38 rabbit monoclonal antibody at 1:1000 dilution. -Lane A: Jurkat Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution. -Developed using the Odyssey technique. -Performed under reducing conditions. -Predicted band size:34 kDa. -Observed band size:50 kDa. 2. CD38 was immunoprecipitated using: -Lane A:0.5 mg Jurkat Whole Cell Lysate. -4µL anti-CD38 rabbit monoclonal antibody and 60 μg of Immunomagnetic beads Protein A/G. -Primary antibody: -Anti-CD38 rabbit monoclonal antibody, at 1:100 dilution. -Secondary antibody: -Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. -Developed using the ECL technique. -Performed under reducing conditions. -Predicted band size: 45 kDa. -Observed band size:45 kDa |
Application | WB,ELISA,IP |
Recommended Dose | WB: 1:2000-1:10000; ELISA: 1:5000-1:10000; IP: 1-5 µL/mg of lysate |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD38 (rh CD38; TMPY-01023; NP_001766.2; Val 43-Ile 300). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 38 (CD38), also known as ADP-ribosyl cyclase, is a glycoprotein found on the surface of many immune cells (white blood cells), including CD4+, CD8+, B and natural killer cells. It shares several characteristics with ADP-ribosyl cyclase 2 CD157. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+to ADP-ribose. It also functions in cell adhesion, signal transduction and calcium signaling. CD38 has been used as a prognostic marker in leukemia. It can also be used to identify plasma cells. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human CD38 protein (TMPY-01023) |
Antigen Species | Human |
Biology Area | Cancer Drug Targets |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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