Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SRD5A1-IN-1 is an inhibitor of steroid 5α-reductase type 1 (SRD5A1, IC50 = 1.44 µM). SRD5A1-IN-1 lowers the production of dihydrotestosterone and shows a significant decrease in the SRD5A1 protein expression.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 195.00 | |
5 mg | In stock | $ 449.00 | |
10 mg | In stock | $ 659.00 | |
25 mg | In stock | $ 987.00 | |
50 mg | In stock | $ 1,390.00 | |
100 mg | In stock | $ 1,880.00 | |
500 mg | In stock | $ 3,780.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 477.00 |
Description | SRD5A1-IN-1 is an inhibitor of steroid 5α-reductase type 1 (SRD5A1, IC50 = 1.44 µM). SRD5A1-IN-1 lowers the production of dihydrotestosterone and shows a significant decrease in the SRD5A1 protein expression. |
In vitro | In HaCaT cells, SRD5A1-IN-1 (0.5-2.5 μM) lowers the expression of SRD5A1 protein and modulates SRD5A1 via the dual actions that affect the level of SRD5A1 protein expression and the activity of the SRD5A1 enzyme. SRD5A1-IN-1 (0.5-2.5 μM) does not affect the mRNA expression of SRD5A1 and shows no significant cytotoxicity[1]. |
Molecular Weight | 391.27 |
Formula | C17H11F6NO3 |
CAS No. | 2279077-93-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 27.5 mg/mL (70.29 mM)
You can also refer to dose conversion for different animals. More
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SRD5A1-IN-1 2279077-93-7 Others SRD5A1IN1 inhibitor inhibit