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Cevostamab
😃Good
Catalog No. T76998Cas No. 2249888-53-5
Alias RO7187797, RO 7187797, RG6160, RG 6160, BFCR4350A, BFCR 4350A
Cevostamab (BFCR4350A; RG6160; RO7187797) is a humanized bispecific antibody targeting FcRH5/CD3. It binds to FcRH5 expressed on multiple myeloma (MM) cells and CD3 on T cells, promoting T cell synapse formation and inhibiting B-cell malignancies.
Cevostamab
Cevostamab
😃Good
Purity: 95%
Catalog No. T76998Alias RO7187797, RO 7187797, RG6160, RG 6160, BFCR4350A, BFCR 4350ACas No. 2249888-53-5
Cevostamab (BFCR4350A; RG6160; RO7187797) is a humanized bispecific antibody targeting FcRH5/CD3. It binds to FcRH5 expressed on multiple myeloma (MM) cells and CD3 on T cells, promoting T cell synapse formation and inhibiting B-cell malignancies.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $290 | - | In Stock | |
| 5 mg | $755 | - | In Stock | |
| 10 mg | $1,200 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:95%
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| Description | Cevostamab (BFCR4350A; RG6160; RO7187797) is a humanized bispecific antibody targeting FcRH5/CD3. It binds to FcRH5 expressed on multiple myeloma (MM) cells and CD3 on T cells, promoting T cell synapse formation and inhibiting B-cell malignancies. |
| In vitro | Cevostamab exhibits potent, dose-dependent killing effects on B cells and bone marrow plasma cells in peripheral blood mononuclear cell (PBMC)/bone marrow monocyte cell (BMMC) samples from rhesus monkeys [1]. |
| In vivo | Cevostamab (0.5 mg/kg; intravenous; weekly) inhibited growth of MOLP-2 tumors in mice reconstituted with human immune cells. |
| Synonyms | RO7187797, RO 7187797, RG6160, RG 6160, BFCR4350A, BFCR 4350A |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal, Bispecific |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | CD3 & FCRL5/CD307e/FcRH5 |
| Cas No. | 2249888-53-5 |
| Color | Transparent |
| Appearance | Liquid |
| Isotype | IgG1 |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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Related Tags: buy Cevostamab | purchase Cevostamab | Cevostamab cost | order Cevostamab | Cevostamab in vivo | Cevostamab in vitro
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