Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Antitumor Agent-73, a derivative of Diosgenin, both impedes STAT3 signaling and exogenously stimulates Pdia3/ERp57. This compound demonstrates significant antineoplastic efficacy, exhibiting potency against diverse cancer cell lines that ranges from 7.9 to 341.7 times that of Diosgenin [1].
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Description | Antitumor Agent-73, a derivative of Diosgenin, both impedes STAT3 signaling and exogenously stimulates Pdia3/ERp57. This compound demonstrates significant antineoplastic efficacy, exhibiting potency against diverse cancer cell lines that ranges from 7.9 to 341.7 times that of Diosgenin [1]. |
In vitro | Antitumor agent-73 (compound 2.2f) exhibits anti-proliferative effects on various cancer cell lines, with IC50 values of 0.1847 μM (Aspc-1), 4.038 μM (H358), 4.001 μM (HCT116), and 0.4483 μM (SW620) [1]. |
Molecular Weight | 858.06 |
Formula | C50H82BrO4P |
CAS No. | 2812356-72-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Antitumor agent-73 2812356-72-0 JAK/STAT signaling Stem Cells STAT inhibitor inhibit