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GSK 789472 hydrochloride

Name: GSK 789472 hydrochloride
Brand: TargetMol
SKU: T22817
Price: 37 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T22817Cas No. 1257326-24-1

Alias GSK-789472 HCl, 4,5-Dihydro-1-phenyl-3-(2-piperidinyl)methylimidazol-2(1H)-one, 1-phenyl-3-(piperidin-2-ylmethyl)imidazolidin-2-one hydrochloride

GSK 789472 hydrochloride is both a dopamine D3 receptor antagonist and a D2 partial agonist.

GSK 789472 hydrochloride

🥰Excellent

Purity: 99.89%

Catalog No. T22817Alias GSK-789472 HCl, 4,5-Dihydro-1-phenyl-3-(2-piperidinyl)methylimidazol-2(1H)-one, 1-phenyl-3-(piperidin-2-ylmethyl)imidazolidin-2-one hydrochlorideCas No. 1257326-24-1

GSK 789472 hydrochloride is both a dopamine D3 receptor antagonist and a D2 partial agonist.

Pack Size	Price	Availability
2 mg	$37	In Stock
5 mg	$62	In Stock
10 mg	$93	In Stock
25 mg	$188	In Stock
50 mg	$273	In Stock
100 mg	$413	In Stock
200 mg	$548	In Stock

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Batch Information

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Purity:99.89%

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COA LCMS HNMR

Product Introduction

Bioactivity

Description	GSK 789472 hydrochloride is both a dopamine D3 receptor antagonist and a D2 partial agonist.
Targets&IC50	D3 receptor:>3.2 μM (EC50), D2 Receptor:5 nM (EC50)
Synonyms	GSK-789472 HCl, 4,5-Dihydro-1-phenyl-3-(2-piperidinyl)methylimidazol-2(1H)-one, 1-phenyl-3-(piperidin-2-ylmethyl)imidazolidin-2-one hydrochloride

Chemical Properties

Molecular Weight	295.81
Formula	C₁₅H₂₂ClN₃O
Cas No.	1257326-24-1
Smiles	Cl.O=C1N(CC2CCCCN2)CCN1c1ccccc1
Relative Density.	no data available
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 7.86 mg/mL (26.57 mM), Sonication is recommended.

H2O: < 30 mg/mL (101.42 mM), Sonication is recommended.

Solution Preparation Table

DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	3.3805 mL	16.9027 mL	33.8055 mL	169.0274 mL
5 mM	0.6761 mL	3.3805 mL	6.7611 mL	33.8055 mL
10 mM	0.3381 mL	1.6903 mL	3.3805 mL	16.9027 mL
20 mM	0.1690 mL	0.8451 mL	1.6903 mL	8.4514 mL

H2O

	1mg	5mg	10mg	50mg
50 mM	0.0676 mL	0.3381 mL	0.6761 mL	3.3805 mL
100 mM	0.0338 mL	0.1690 mL	0.3381 mL	1.6903 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc