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Norhyodeoxycholic Acid

Name: Norhyodeoxycholic Acid
Brand: TargetMol
SKU: T37178
Rating: 4.5 (1 reviews)

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Catalog No. T37178Cas No. 77518-23-1

Norhyodeoxycholic acid (NHDCA) is a synthetic bile acid and a derivative of hyodeoxycholic acid .1,2 NHDCA is an intermediate in the synthesis of 3β-sulfooxy-7β-hydroxy-24-nor-5-cholen-23-oic acid, which has been used as an internal standard for the quantification of δ5-bile acid conjugates that have been identified in patients with Niemann-Pick disease type C1.3

Norhyodeoxycholic Acid

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Catalog No. T37178Cas No. 77518-23-1

Pack Size	Price	Availability
1 mg	TBD	35 days
5 mg	TBD	35 days
10 mg	TBD	35 days

Bulk & Custom

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

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Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	378.553
Formula	C₂₃H₃₈O₄
Cas No.	77518-23-1
Relative Density.	1.142 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMF: 30 mg/mL (79.25 mM), Sonication is recommended.

Ethanol: 20 mg/mL (52.83 mM), Sonication is recommended.

DMSO: 20 mg/mL (52.83 mM), Sonication is recommended.

DMF:PBS (pH 7.2) (1:1): 0.5 mg/mL (1.32 mM), Sonication is recommended.

Solution Preparation Table

Ethanol/DMSO/DMF

	1mg	5mg	10mg	50mg
5 mM	0.5283 mL	2.6416 mL	5.2833 mL	26.4164 mL
10 mM	0.2642 mL	1.3208 mL	2.6416 mL	13.2082 mL
20 mM	0.1321 mL	0.6604 mL	1.3208 mL	6.6041 mL
50 mM	0.0528 mL	0.2642 mL	0.5283 mL	2.6416 mL

Calculator

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Norhyodeoxycholic Acid