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Bruceine E

Name: Bruceine E
Brand: TargetMol
SKU: TN1128
Price: 46 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN1128Cas No. 21586-90-3

Bruceine E is isolated from B. javanica seeds with hypoglycemia effects. Bruceine E can be used for studies about acting as an insulin secretagogue.

Bruceine E

🥰Excellent

Purity: 99.88%

Catalog No. TN1128Cas No. 21586-90-3

Bruceine E is isolated from B. javanica seeds with hypoglycemia effects. Bruceine E can be used for studies about acting as an insulin secretagogue.

Pack Size	Price	Availability
1 mg	$46	In Stock
5 mg	$107	In Stock
10 mg	$163	In Stock
25 mg	$275	In Stock
50 mg	$398	In Stock
100 mg	$556	In Stock
200 mg	$755	In Stock
1 mL x 10 mM (in DMSO)	$125	In Stock

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Batch Information

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Purity:99.88%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Bruceine E is isolated from B. javanica seeds with hypoglycemia effects. Bruceine E can be used for studies about acting as an insulin secretagogue.
In vitro	Bruceine E exhibits significant blood glucose concentration reduction activity[1].
In vivo	Bruceine E (1 mg/kg b.w.) exhibits blood glucose lowering effect in both nondiabetic mice and Streptozotocin (STZ)-induced diabetic rats at lower dose[3].

Chemical Properties

Molecular Weight	412.43
Formula	C₂₀H₂₈O₉
Cas No.	21586-90-3
Smiles	O[C@]12[C@@]34[C@@]([C@]5(C)[C@@](C[C@]3(OC(=O)[C@@H]1O)[H])(C(C)=C[C@H](O)[C@H]5O)[H])([C@@H](O)[C@H](O)[C@@]2(C)OC4)[H]
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (121.23 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4247 mL	12.1233 mL	24.2465 mL	121.2327 mL
5 mM	0.4849 mL	2.4247 mL	4.8493 mL	24.2465 mL
10 mM	0.2425 mL	1.2123 mL	2.4247 mL	12.1233 mL
20 mM	0.1212 mL	0.6062 mL	1.2123 mL	6.0616 mL
50 mM	0.0485 mL	0.2425 mL	0.4849 mL	2.4247 mL
100 mM	0.0242 mL	0.1212 mL	0.2425 mL	1.2123 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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