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Ganodermanondiol
🥰Excellent
Catalog No. TN1670Cas No. 107900-76-5
Ganodermanondiol is a natural melanogenesis inhibitor capable of suppressing tyrosinase, TRP-1, TRP-2, and MITF in B16F10 cells, while influencing MAPK and cAMP pathways. It also exhibits anti-inflammatory and hepatoprotective effects by modulating Nrf2-dependent HO-1 and AMPK.
Ganodermanondiol
🥰Excellent
Catalog No. TN1670Cas No. 107900-76-5
Ganodermanondiol is a natural melanogenesis inhibitor capable of suppressing tyrosinase, TRP-1, TRP-2, and MITF in B16F10 cells, while influencing MAPK and cAMP pathways. It also exhibits anti-inflammatory and hepatoprotective effects by modulating Nrf2-dependent HO-1 and AMPK.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $176 | - | In Stock | |
| 5 mg | $533 | - | In Stock | |
| 10 mg | $758 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
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Chemical Properties
| Description | Ganodermanondiol is a natural melanogenesis inhibitor capable of suppressing tyrosinase, TRP-1, TRP-2, and MITF in B16F10 cells, while influencing MAPK and cAMP pathways. It also exhibits anti-inflammatory and hepatoprotective effects by modulating Nrf2-dependent HO-1 and AMPK. |
| Targets&IC50 | HIV-1 protease:90μM |
| In vitro | Ganodermanondiol significantly increased the survival rate of HepG2 cells and inhibited t-BHP-induced ROS generation at non-cytotoxic concentrations (5, 10, 20, 40 μM). [1] |
| Molecular Weight | 456.7 |
| Formula | C30H48O3 |
| Cas No. | 107900-76-5 |
| Smiles | C[C@@]12C=3C([C@@]4(C)[C@](C)(CC3)[C@@]([C@@H](CC[C@@H](C(C)(C)O)O)C)(CC4)[H])=CC[C@]1(C(C)(C)C(=O)CC2)[H] |
| Relative Density. | 1.07g/cm3 |
| Color | White |
| Appearance | Solid |
Storage & Solubility Information
| Storage | keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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