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Anti-Syndecan-1 Antibody (1I989)
🥰Excellent
Catalog No. TMAY-01863
Anti-Syndecan-1 Antibody (1I989) is a Rabbit antibody targeting Syndecan-1. Anti-Syndecan-1 Antibody (1I989) can be used in ELISA,FCM.
Anti-Syndecan-1 Antibody (1I989)
Anti-Syndecan-1 Antibody (1I989)
🥰Excellent
Catalog No. TMAY-01863
Anti-Syndecan-1 Antibody (1I989) is a Rabbit antibody targeting Syndecan-1. Anti-Syndecan-1 Antibody (1I989) can be used in ELISA,FCM.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Syndecan-1 Antibody (1I989) is a Rabbit antibody targeting Syndecan-1. Anti-Syndecan-1 Antibody (1I989) can be used in ELISA,FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 1I989 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of Human SDC1(CD138) expression on RPMI8226 cells. Cells were stained with purified anti-Human SDC1(CD138), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| Application | ELISA,FCM |
| Recommended Dose | ELISA: 1:5000-1:10000; FCM: 1:25-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human Syndecan-1/CD138/SDC1 (rh Syndecan-1/CD138/SDC1; TMPY-01630; NP_002988.3; Met1-Glu251). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Syndecan-1 also known as SDC1 and CD138, is the most extensively studied member of the syndecan family. It is found mainly in epithelial cells, but its expression is developmentally regulated during embryonic development. Syndecan-1/SDC1/CD138 has been shown to mediate cell adhesion to several ECM molecules, and to act as a coreceptor for fibroblast growth factors, potent angiogenic growth factors involved also in differentiation. Syndecan-1/SDC1/CD138 expression is reduced during malignant transformation of various epithelia, and this loss correlates with the histological differentiation grade of squamous cell carcinomas, lacking from poorly differentiated tumours. In squamous cell carcinomas of the head and neck, positive syndecan-1 expression correlates with a more favourable prognosis. Experimental studies on the role of Syndecan-1 in malignant transformation have shown that Syndecan-1/SDC1/CD138 expression is associated with the maintenance of epithelial morphology, anchorage-dependent growth and inhibition of invasiveness in vitro. |
| Conjucates | Unconjugated |
| Others Formats | APC/PerCP/FITC/PE |
| Antibody Types Available | 5 |
| Immunogen | Recombinant Human Syndecan-1/CD138/SDC1 Protein (TMPY-01630) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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