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BT1769 is a bicyclic toxin conjugate targeting MT1-MMP (Matrilysin 1 type-MMP) with a KD of 3.35 nM. It is utilized for osteosarcoma research. BT1769 comprises an innovative bicyclic targeting peptide that selectively binds to MT1-MMP, a cytotoxin MMAE, and a dipeptide linker that can be enzymatically cleaved.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | Inquiry | Inquiry | |
| 50 mg | Inquiry | Inquiry | Inquiry |
| Description | BT1769 is a bicyclic toxin conjugate targeting MT1-MMP (Matrilysin 1 type-MMP) with a KD of 3.35 nM. It is utilized for osteosarcoma research. BT1769 comprises an innovative bicyclic targeting peptide that selectively binds to MT1-MMP, a cytotoxin MMAE, and a dipeptide linker that can be enzymatically cleaved. |
| Molecular Weight | 3939.45 |
| Formula | C186H269N43O50S |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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