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COX-2-IN-43

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Catalog No. T86084Cas No. 1023524-40-4

COX-2-IN-43 (Compound MYM4) functions as a selective COX-2 inhibitor, exhibiting IC50 values of 0.983 μM for COX-1 and 0.247 μM for COX-2. It effectively inhibits cancer cell proliferation and colonization and also induces apoptosis [1].

COX-2-IN-43

COX-2-IN-43

😃Good
Catalog No. T86084Cas No. 1023524-40-4
COX-2-IN-43 (Compound MYM4) functions as a selective COX-2 inhibitor, exhibiting IC50 values of 0.983 μM for COX-1 and 0.247 μM for COX-2. It effectively inhibits cancer cell proliferation and colonization and also induces apoptosis [1].
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
10 mgInquiry10-14 weeks10-14 weeks
50 mgInquiry10-14 weeks10-14 weeks
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
COX-2-IN-43 (Compound MYM4) functions as a selective COX-2 inhibitor, exhibiting IC50 values of 0.983 μM for COX-1 and 0.247 μM for COX-2. It effectively inhibits cancer cell proliferation and colonization and also induces apoptosis [1].
Targets&IC50
COX-1:14.86 μM, COX-2:0.247 μM
In vitro
COX-2-IN-43 inhibits the proliferation of CaCo-2, Hep3B, and HeLa cancer cells, with IC50 values of 10.22, 4.84, and 1.57 μM, respectively [1].
Chemical Properties
Molecular Weight431.19
FormulaC18H11Cl2F3N2O3
Cas No.1023524-40-4
SmilesC(NC1=CC=C(OC(F)(F)F)C=C1)(=O)C=2C(=NOC2C)C3=C(Cl)C=CC=C3Cl
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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