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Anti-B7-1 Antibody-Biotin (4I630) (Synonyms: CD80 molecule)

Catalog No. TMAY-01080B Copy Product Info
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Anti-B7-1 Antibody-Biotin (4I630) is a Biotin-conjugated Mouse antibody targeting B7-1. Anti-B7-1 Antibody-Biotin (4I630) can be used in ELISA.

Anti-B7-1 Antibody-Biotin (4I630)

Copy Product Info
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Catalog No. TMAY-01080B
Synonyms CD80 molecule

Anti-B7-1 Antibody-Biotin (4I630) is a Biotin-conjugated Mouse antibody targeting B7-1. Anti-B7-1 Antibody-Biotin (4I630) can be used in ELISA.

Anti-B7-1 Antibody-Biotin
(4I630)
Pack SizePriceUSA StockGlobal StockQuantity
20 μg$927-10 days7-10 days
100 μg$2937-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-B7-1 Antibody-Biotin (4I630) is a Biotin-conjugated Mouse antibody targeting B7-1. Anti-B7-1 Antibody-Biotin (4I630) can be used in ELISA.
SynonymsCD80 molecule
Ig Type
Mouse IgG1
Clone
4I630
Reactivity
Human
Specificity
Human B7-1/CD80
Application
ELISA
Recommended Dose
ELISA: 0.1-1 μg/ml
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD80 / B7-1 (rh CD80 / B7-1; TMPY-01063; Met 1-Asn 242; NP_005182.1). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography and then biotinylated.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundThe B-lymphocyte activation antigen B7-1 (referred to as B7), also known as CD80, is a member of cell surface immunoglobulin superfamily and is expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells. As costimulatory ligands, B7-1 which exists predominantly as dimer and the related protein B7-2, interact with the costimulatory receptors CD28 and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expressed on T cells, and thus constitute one of the dominant pathways that regulate T cell activation and tolerance, cytokine production, and the generation of CTL. The B7/CD28/CTLA4 pathway has the ability to both positively and negatively regulate immune responses. CD80 is thus regarded as promising therapeutic targets for autoimmune diseases and various carcinomas.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: IHC AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy
Related Conjugates and Formulations
Conjucates
Biotin
Others Formats
Unconjugated/FITC/PE
Antibody Types Available
4
Antigen Details
Immunogen
Recombinant Protein: Human CD80 / B7-1 Protein (TMPY-01063)
Antigen Species
Human
Biology Area
Cancer Drug Targets
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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