Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ATAC21 is a linker-immune-stimulatory compound created by conjugating a noncleavable maleimide-PEG4 linker, which includes a succinimide group, with an immune-stimulatory agent. This compound can be further conjugated with SBT-040 (anti-CD40 antibody) to form a conjugate [1].
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50 mg | Inquiry | Inquiry |
Description | ATAC21 is a linker-immune-stimulatory compound created by conjugating a noncleavable maleimide-PEG4 linker, which includes a succinimide group, with an immune-stimulatory agent. This compound can be further conjugated with SBT-040 (anti-CD40 antibody) to form a conjugate [1]. |
In vitro | A recombinant bispecific antibody comprises: a) a target antigen-binding domain that specifically binds to a tumor-associated antigen; b) an effector antigen-binding domain that specifically binds to an antigen on antigen-presenting cells, where the antigen is a molecule on the surface of antigen-presenting cells; c) an Fc-containing domain; and d) an immune-stimulatory compound linked to the recombinant bispecific antibody through a linker. This recombinant bispecific antibody, when bound to both the tumor-associated antigen and the antigen on antigen-presenting cells as opposed to only the latter, elicits greater immune cell activation. However, it does not target the tumor-associated antigen [1]. |
Molecular Weight | 1072.82 |
Formula | C38H50N12O21P2 |
CAS No. | 2101204-23-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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ATAC21 2101204-23-1 inhibitor inhibit