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Anti-ALK-1 Antibody (3M872)
😃Good
Catalog No. TMAH-00025
Alias TSR-I, SKR3, ORW2, HHT2, HHT, ALK-1, ALK1, ACVRLK1, ACVRL1, activin A receptor type II-like 1
Anti-ALK-1 Antibody (3M872) is an antibody targeting ALK-1. Anti-ALK-1 Antibody (3M872) can be used in ELISA.
Anti-ALK-1 Antibody (3M872)
Anti-ALK-1 Antibody (3M872)
😃Good
Catalog No. TMAH-00025Alias TSR-I, SKR3, ORW2, HHT2, HHT, ALK-1, ALK1, ACVRLK1, ACVRL1, activin A receptor type II-like 1
Anti-ALK-1 Antibody (3M872) is an antibody targeting ALK-1. Anti-ALK-1 Antibody (3M872) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | 198 € | 7-10 days | |
| 100 μL | 330 € | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-ALK-1 Antibody (3M872) is an antibody targeting ALK-1. Anti-ALK-1 Antibody (3M872) can be used in ELISA. |
| Alias | TSR-I, SKR3, ORW2, HHT2, HHT, ALK-1, ALK1, ACVRLK1, ACVRL1, activin A receptor type II-like 1 |
| Ig Type | Human IgG2 |
| Clone | 3M872 |
| Reactivity | Human |
| Verified Activity | 1. The Binding Activity of Human ACVRL1 with Anti-ACVRL1 recombinant antibody Activity: Measured by its binding ability in a functional ELISA. Immobilized Human ACVRL1 at 2 μg/mL can bind Anti-ACVRL1 recombinant antibody, the EC50 is 2.417-2.971ng/mL. 2. The Binding Activity of Cynomolgus ACVRL1 with Anti-ACVRL1 recombinant antibody Activity: Measured by its binding ability in a functional ELISA.Immobilized Cynomolgus ACVRL1 at 2 μg/mL can bind Anti-ACVRL1 recombinant antibody. The EC50 is 6.893-8.194 ng/mL. |
| Application | ELISA |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cell membrane; Single-pass type I membrane protein. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
| Research Background | Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human ACVRL1 Protein |
| Antigen Species | Human |
| Gene ID | 94 |
| Uniprot ID | |
| Biology Area | Immunology, Stem cells |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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