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6-Demethoxytangeretin

🥰Excellent
Catalog No. T8152Cas No. 6601-66-7

6-Demethoxytangeretin, a citrus flavonoid isolated from Citrus depressa.

6-Demethoxytangeretin

6-Demethoxytangeretin

🥰Excellent
Purity: 99.89%
Catalog No. T8152Cas No. 6601-66-7
6-Demethoxytangeretin, a citrus flavonoid isolated from Citrus depressa.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$54In StockIn Stock
5 mg$127In StockIn Stock
10 mg$198In StockIn Stock
25 mg$347In StockIn Stock
50 mg$515In StockIn Stock
100 mg$733-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.89%
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COA HNMR HPLC

Product Introduction

Bioactivity
Description
6-Demethoxytangeretin, a citrus flavonoid isolated from Citrus depressa.
In vitro
6-Demethoxytangeretin exerts anti-inflammatory activity and anti-allergic activity, suppresses production and gene expression of interleukin-6 in human mast cell-1 via ALK and MAPK pathways [1]. 6-Demethoxytangeretin facilitates the Cre-mediated transcription associated with learning and memory in cultured hippocampal neurons [2].
Chemical Properties
Molecular Weight342.34
FormulaC19H18O6
Cas No.6601-66-7
SmilesCOc1ccc(cc1)-c1cc(=O)c2c(OC)cc(OC)c(OC)c2o1
Relative Density.1.243 g/cm3 (Predicted)
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 3.43 mg/mL (10.02 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.9211 mL14.6054 mL29.2107 mL146.0536 mL
5 mM0.5842 mL2.9211 mL5.8421 mL29.2107 mL
10 mM0.2921 mL1.4605 mL2.9211 mL14.6054 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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Keywords

MAPKInhibitorinhibitCluster of differentiation 246CD246Anaplastic lymphoma kinase (ALK)Anaplastic lymphoma kinaseALK tyrosine kinase receptorALK6-Demethoxytangeretin6Demethoxytangeretin6 Demethoxytangeretin
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