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Citric acid
🥰Excellent
Catalog No. T5S0636Cas No. 77-92-9
Alias Citro, Citretten
Citric acid (Citro) is a weak organic tricarboxylic acid found in citrus fruits. Citric acid is a food additive and a natural preservative.
Citric acid
🥰Excellent
Purity: 98.88%
Catalog No. T5S0636Alias Citro, CitrettenCas No. 77-92-9
Citric acid (Citro) is a weak organic tricarboxylic acid found in citrus fruits. Citric acid is a food additive and a natural preservative.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 500 mg | $38 | In Stock | |
| 1 g | $54 | In Stock | |
| 5 g | $129 | In Stock | |
| 10 g | $189 | In Stock | |
| 25 g | $319 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $44 | In Stock |
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Purity:98.88%
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Product Introduction
Bioactivity
Chemical Properties
| Description | Citric acid (Citro) is a weak organic tricarboxylic acid found in citrus fruits. Citric acid is a food additive and a natural preservative. |
| Targets&IC50 | GF:0.28 per cent, HaCaT cells:12.5 mM |
| In vitro | METHODS: HaCaT cells were treated with Citric acid (0-12.5 mM) for 24 hours, and the percentage of viable cells was determined by flow cytometry. RESULTS: Citric acid exhibited anti-proliferative activity in a dose-dependent manner. [1] METHODS: HaCaT cells were treated with Citric acid (12.5 mM) for 48 hours, and the levels of related proteins were detected by western blot. RESULTS: Citric acid increased the expressions of FAS, BAX, BID, AIF, EndoG, cytochrome C, PARP, GADD153, GRP78 and Caspase-3, -8, -9, and decreased the expressions of BCL-2 and BCL-Xl. [1] |
| In vivo | METHODS: To study the effect of Citric acid on the liver of mice, Citric acid (120, 240, and 480 mg/kg) was intraperitoneally injected into mice. RESULTS: Citric acid significantly reduced the activity of GSH-Px in the liver of mice, induced an increase in the level of MDA (malondialdehyde), and increased the activity of caspase-3 to induce apoptosis in a dose-dependent manner. [2] METHODS: To study the nephrotoxicity of Citric acid, Citric acid (120, 240, and 480 mg/kg) was intraperitoneally injected into mice every week for 3 consecutive weeks. RESULTS: Citric acid causes nephrotoxicity in mice. [3] |
| Synonyms | Citro, Citretten |
| Molecular Weight | 192.12 |
| Formula | C6H8O7 |
| Cas No. | 77-92-9 |
| Smiles | OC(=O)CC(O)(CC(O)=O)C(O)=O |
| Relative Density. | 1.67. Temperature:20 °C. |
| Color | White |
| Appearance | Solid |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | H2O: 100 mg/mL (520.51 mM), Sonication is recommended.  DMSO: 240 mg/mL (1249.22 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
H2O/DMSO
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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