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Aflatoxin G1

Name: Aflatoxin G1
Brand: TargetMol
SKU: TN1359
Rating: 4.5 (1 reviews)

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Catalog No. TN1359Cas No. 1165-39-5

Aflatoxin G1 is a mycotoxin produced by Aspergillus flavus and Aspergillus parasiticus, which is hepatotoxic, teratogenic, immunosuppressive, and carcinogenic, and is mainly found in contaminated cereals. Aflatoxin G1 inhibits RNA polymerase activity, affects RNA and protein synthesis, and causes damage to the liver and kidney.

Aflatoxin G1

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Catalog No. TN1359Cas No. 1165-39-5

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 mg	$232	7-10 days	7-10 days
1 mL x 10 mM (in DMSO)	$600	7-10 days	7-10 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Appearance:Solid

Color:White

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COA

Product Introduction

Bioactivity

Description

In vitro

Aflatoxin G1 was removed from liquid cultures by growing and resting cells of Flavobacterium aurantiacum NRRL B-184. In inoculated culture media containing toxin levels of 7.5 p.p.m. and above, there was a protracted growth lag which was subsequently overcome; toxin removal then occurred, concomitant with growth. Only a few cells demonstrated aberrant morphological forms when cultured in the presence of Aflatoxin G1. A comparison of the effects of Aflatoxin G1 with B1 on growth and morphology showed that B1 was distinctly more toxic[1]

Chemical Properties

Molecular Weight	328.27
Formula	C₁₇H₁₂O₇
Cas No.	1165-39-5
Smiles	O(C)C=1C2=C(C3=C(O[C@@]4([C@]3(C=CO4)[H])[H])C1)OC(=O)C5=C2CCOC5=O
Relative Density.	1.3358 g/cm3 (Estimated)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 8 mg/mL (24.37 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.0463 mL	15.2314 mL	30.4627 mL	152.3136 mL
5 mM	0.6093 mL	3.0463 mL	6.0925 mL	30.4627 mL
10 mM	0.3046 mL	1.5231 mL	3.0463 mL	15.2314 mL
20 mM	0.1523 mL	0.7616 mL	1.5231 mL	7.6157 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc