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Nodakenetin

Name: Nodakenetin
Brand: TargetMol
SKU: T5S1413
Price: 123 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T5S1413Cas No. 495-32-9

Alias Prangeferol, Nodakenitin, (-)-Prangeferol

1. Nodakenetin ((-)-Prangeferol) has clinical efficacy.

Nodakenetin

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Purity: 99.97%

Catalog No. T5S1413Alias Prangeferol, Nodakenitin, (-)-PrangeferolCas No. 495-32-9

1. Nodakenetin ((-)-Prangeferol) has clinical efficacy.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$123	In Stock	In Stock
5 mg	$372	In Stock	In Stock
10 mg	$548	In Stock	In Stock
25 mg	$869	In Stock	In Stock
50 mg	$1,170	-	In Stock
100 mg	$1,570	-	In Stock
1 mL x 10 mM (in DMSO)	$346	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.97%

Appearance:Solid

Color:White

Resource Download

COA HNMR HPLC

Product Introduction

Nodakenetin AI Summary

Nodakenetin exhibits a range of bioactivities based on the research data: It shows potency as a reactivator of NPC1 Promoter Activators, with a potency of 2511.9 nM. It demonstrates potency as both an inhibitor and activator of various enzymes and cellular processes associated with diseases like Gaucher Disease and cellular repair mechanisms. It also displays activity as an inhibitor of the malarial parasite plastid and various other cellular targets. Overall, Nodakenetin appears to have diverse bioactivities across different cellular pathways and disease models..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	1. Nodakenetin ((-)-Prangeferol) has clinical efficacy.
Synonyms	Prangeferol, Nodakenitin, (-)-Prangeferol

Chemical Properties

Molecular Weight	246.26
Formula	C₁₄H₁₄O₄
Cas No.	495-32-9
Smiles	CC(C)(O)[C@H]1Cc2cc3ccc(=O)oc3cc2O1
Relative Density.	1.334g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 65 mg/mL (263.95 mM), Sonication is recommended.

Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (8.12 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.0607 mL	20.3037 mL	40.6075 mL	203.0374 mL
5 mM	0.8121 mL	4.0607 mL	8.1215 mL	40.6075 mL
10 mM	0.4061 mL	2.0304 mL	4.0607 mL	20.3037 mL
20 mM	0.2030 mL	1.0152 mL	2.0304 mL	10.1519 mL
50 mM	0.0812 mL	0.4061 mL	0.8121 mL	4.0607 mL
100 mM	0.0406 mL	0.2030 mL	0.4061 mL	2.0304 mL

Calculator

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc