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ε-Viniferin

Name: ε-Viniferin
Brand: TargetMol
SKU: T11218
Price: 228 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T11218Cas No. 62218-08-0

Alias epsilon-Viniferin

ε-Viniferin (epsilon-Viniferin) a dimer of resveratrol, shows the inhibitory effects of epsilon-viniferin on human CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2B6, CYP2E1, CYP3A4 and CYP4A activities.

ε-Viniferin

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Purity: 99.98%

Catalog No. T11218Alias epsilon-ViniferinCas No. 62218-08-0

ε-Viniferin (epsilon-Viniferin) a dimer of resveratrol, shows the inhibitory effects of epsilon-viniferin on human CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2B6, CYP2E1, CYP3A4 and CYP4A activities.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$228	In Stock	In Stock
5 mg	$768	In Stock	In Stock
10 mg	$1,080	In Stock	In Stock
25 mg	$1,580	In Stock	In Stock
50 mg	$2,150	In Stock	In Stock
100 mg	$2,880	-	In Stock
1 mL x 10 mM (in DMSO)	$888	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.98%

Appearance:Solid

Color:Yellow

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COA LCMS

Product Introduction

ε-Viniferin AI Summary

ε-Viniferin exhibits a range of biological activities, including antifungal, estrogenic, enzymatic, and antiviral effects. - **Antifungal Activity**: It inhibits the growth of several fungi, such as Diplodia seriata, Lasiodiplodia theobromae, Diplodia mutila, Neofusicoccum luteum, Neofusicoccum parvum, and Botryosphaeria dothidea, with growth inhibition percentages ranging from 14.0% to 24.0% over 1 to 10 days. Specifically, for Diplodia seriata, it has an IC50 value of 260000.0 nM. - **Estrogenic Activity**: It enhances estrogen receptor (ER)-mediated transcriptional activation in human HepG2 cells. At 1 uM concentration, it shows a fold change (FC) of 1.0, and at 10 uM, an FC of 1.1, indicating estrogenic effects through ERalpha/ERbeta pathways. - **Enzymatic Inhibition**: It inhibits human recombinant monoamine oxidase A (MAO-A) with an IC50 value of 19600.0 nM in assays using p-tyramine as a substrate. - **Antiviral Activity**: It demonstrates effective antiviral activity against strains of Influenza A virus and Hepatitis C virus, with EC50 values indicative of its ability to inhibit RANTES production and reduce viral replication. It also shows cytotoxicity with CC50 values higher than the effective antiviral concentrations, indicating selective antiviral activity..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	ε-Viniferin (epsilon-Viniferin) a dimer of resveratrol, shows the inhibitory effects of epsilon-viniferin on human CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2B6, CYP2E1, CYP3A4 and CYP4A activities.
Targets&IC50	CYP1A2:5 μM （Ki,EROD）, CYP2B6:3 μM （Ki,BROD）, CYP4A:15 μM(LwOH), CYP2E1:25 μM (CHZ), CYP2A6:60 μM （Ki,COH）, CYP3A4:10 μM （Ki,TST）
Synonyms	epsilon-Viniferin

Chemical Properties

Molecular Weight	454.47
Formula	C₂₈H₂₂O₆
Cas No.	62218-08-0
Smiles	Oc1ccc(\C=C\c2cc(O)cc3O[C@H]([C@@H](c23)c2cc(O)cc(O)c2)c2ccc(O)cc2)cc1
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 75 mg/mL (165.03 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween-80+45% Saline: 1.67 mg/mL (3.67 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2004 mL	11.0018 mL	22.0037 mL	110.0183 mL
5 mM	0.4401 mL	2.2004 mL	4.4007 mL	22.0037 mL
10 mM	0.2200 mL	1.1002 mL	2.2004 mL	11.0018 mL
20 mM	0.1100 mL	0.5501 mL	1.1002 mL	5.5009 mL
50 mM	0.0440 mL	0.2200 mL	0.4401 mL	2.2004 mL
100 mM	0.0220 mL	0.1100 mL	0.2200 mL	1.1002 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc