Nigranoic acid

Name: Nigranoic acid
Brand: TargetMol
SKU: T13796
Rating: 4.5 (1 reviews)

🥰Excellent

Catalog No. T13796Cas No. 39111-07-4

Nigranoic acid is a natural product,and inhibits HIV-1 reverse transcriptase.

Nigranoic acid

🥰Excellent

Catalog No. T13796Cas No. 39111-07-4

Nigranoic acid is a natural product,and inhibits HIV-1 reverse transcriptase.

Product information is being updated, if you want to purchase, please click the bulk custom button.

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Product Introduction

Bioactivity

Description	Nigranoic acid is a natural product,and inhibits HIV-1 reverse transcriptase.
In vivo	Nigranoic acid significantly protects against rat cerebral ischemia-reperfusion injury by downregulating nerve cell apoptosis through the inhibition of PARP overactivation and AIF nuclear translocation[1].

Chemical Properties

Molecular Weight	470.68
Formula	C₃₀H₄₆O₄
Cas No.	39111-07-4
Smiles	[H][C@@]1(CC[C@@]2(C)[C@]3([H])CC[C@@H](C(C)=C)[C@@]4(CCC(O)=O)C[C@@]34CC[C@]12C)[C@H](C)CC\C=C(\C)C(O)=O
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline /PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline /PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc