Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Anticancer agent 135 (compound 26h) acts as a potent androgen receptor (AR) antagonist, effectively blocking AR nuclear translocation and inhibiting AR/AR-V7 heterodimerization to suppress downstream gene transcription. This compound demonstrates strong efficacy in prostate cancer xenograft models [1].
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Description | Anticancer agent 135 (compound 26h) acts as a potent androgen receptor (AR) antagonist, effectively blocking AR nuclear translocation and inhibiting AR/AR-V7 heterodimerization to suppress downstream gene transcription. This compound demonstrates strong efficacy in prostate cancer xenograft models [1]. |
Molecular Weight | 458.5 |
Formula | C23H21F3N4OS |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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Anticancer agent 135 Endocrinology/Hormones Androgen Receptor inhibitor inhibit