Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TNKS-2-IN-1 is a TNKS-2 inhibitor.TNKS-2-IN-1 inhibits TNKS-1 and TNKS-2 with IC50s of 259 nM and 1100 nM, respectively.TNKS-2-IN-1 has antimicrobial activity against E. coli and S. aureus.TNKS-2-IN-1 inhibits the release of IL-1β from the NLRP3 inflammasome (IC50: 5 μM) by inhibiting IL-1β release from ATP-stimulated J1A.774 cells.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 mg | In stock | $ 30.00 | |
25 mg | In stock | $ 50.00 | |
50 mg | In stock | $ 98.00 |
Description | TNKS-2-IN-1 is a TNKS-2 inhibitor.TNKS-2-IN-1 inhibits TNKS-1 and TNKS-2 with IC50s of 259 nM and 1100 nM, respectively.TNKS-2-IN-1 has antimicrobial activity against E. coli and S. aureus.TNKS-2-IN-1 inhibits the release of IL-1β from the NLRP3 inflammasome (IC50: 5 μM) by inhibiting IL-1β release from ATP-stimulated J1A.774 cells. |
Targets&IC50 | TNKS1:259 nM, TNKS2:1100 nM |
Molecular Weight | 267.24 |
Formula | C14H9N3O3 |
CAS No. | 4765-59-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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TNKS-2-IN-1 4765-59-7 Chromatin/Epigenetic Cytoskeletal Signaling DNA Damage/DNA Repair Microbiology/Virology Stem Cells Antibiotic PARP Wnt/beta-catenin TNKS2IN1 inhibitor inhibit