Powder: -20°C for 3 years | In solvent: -80°C for 1 year
KBC-007 is a synthetic branched chain-containing analog of α-galactosylceramide (α-GalCer). It induces IL-4 and IFN-γ secretion by mouse splenocytes when used at a concentration of 0.5 ng/ml and IL-2 secretion by DN32.D3 NKT hybridoma cells co-cultured with CD1d-transfected RBL cells pre-loaded with KBC-007 at a concentration of 8 ng/ml. KBC-007 (1 μg per animal) increases levels of IL-4, but not IFN-γ, to a similar degree as α-GalCer in mouse serum. KBC-007 (0.5 μg per animal) increases the survival rate of mice immunized with the inactivated influenza A virus A/PR/8/34 in a model of influenza infection.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | Inquiry | $ 1,398.00 |
Description | KBC-007 is a synthetic branched chain-containing analog of α-galactosylceramide (α-GalCer). It induces IL-4 and IFN-γ secretion by mouse splenocytes when used at a concentration of 0.5 ng/ml and IL-2 secretion by DN32.D3 NKT hybridoma cells co-cultured with CD1d-transfected RBL cells pre-loaded with KBC-007 at a concentration of 8 ng/ml. KBC-007 (1 μg per animal) increases levels of IL-4, but not IFN-γ, to a similar degree as α-GalCer in mouse serum. KBC-007 (0.5 μg per animal) increases the survival rate of mice immunized with the inactivated influenza A virus A/PR/8/34 in a model of influenza infection. |
Molecular Weight | 817.247 |
Formula | C46H92N2O9 |
CAS No. | 1037297-61-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 12 mg/mL
DMSO: 20 mg/mL
H2O: 18 mg/mL
You can also refer to dose conversion for different animals. More
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KBC-007 1037297-61-2 KBC 007 KBC007 inhibitor inhibit