Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Isovaleryl-L-carnitine is a naturally occurring acylcarnitine that is formed via metabolic conversion of L-leucine. It increases survival and decreases apoptosis in hepatocyte growth factor-deprived murine C2.8 hepatocytes when used at a concentration of 1 mM. Isovaleryl-L-carnitine inhibits amino acid deprivation-induced proteolysis and autophagy in isolated perfused rat liver when used at concentrations of 77 and 100 μM, respectively. Increased levels of isovaleryl carnitine are associated with isovaleryl-CoA dehydrogenase deficiency (isovaleric acidemia).
Description | Isovaleryl-L-carnitine is a naturally occurring acylcarnitine that is formed via metabolic conversion of L-leucine. It increases survival and decreases apoptosis in hepatocyte growth factor-deprived murine C2.8 hepatocytes when used at a concentration of 1 mM. Isovaleryl-L-carnitine inhibits amino acid deprivation-induced proteolysis and autophagy in isolated perfused rat liver when used at concentrations of 77 and 100 μM, respectively. Increased levels of isovaleryl carnitine are associated with isovaleryl-CoA dehydrogenase deficiency (isovaleric acidemia). |
Molecular Weight | 281.78 |
Formula | C12H24ClNO4 |
CAS No. | 139144-12-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PBS (pH 7.2): 10 mg/mL
Ethanol: 25 mg/mL
DMSO: 20 mg/mL
DMF: 15 mg/mL
You can also refer to dose conversion for different animals. More
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Isovaleryl-L-carnitine (chloride) 139144-12-0 IsovalerylLcarnitine (chloride) Isovaleryl-L-carnitine Isovaleryl L carnitine (chloride) inhibitor inhibit