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AXC-715 trihydrochloride

🥰Excellent
Catalog No. T72253Cas No. 2479276-17-8
Alias T785 trihydrochloride

AXC-715 trihydrochloride (T785 trihydrochloride) is a TLR7/TLR8 dual agonist for the synthesis of antibody-adjuvanted immunocouplings. The couplings are mostly programmed death ligand 1 (PD-L1) attached to one or more antibody structures of the adjuvant.

AXC-715 trihydrochloride
Other Forms of AXC-715 trihydrochloride:

AXC-715 trihydrochloride

🥰Excellent
Purity: 99.74%
Catalog No. T72253Alias T785 trihydrochlorideCas No. 2479276-17-8
AXC-715 trihydrochloride (T785 trihydrochloride) is a TLR7/TLR8 dual agonist for the synthesis of antibody-adjuvanted immunocouplings. The couplings are mostly programmed death ligand 1 (PD-L1) attached to one or more antibody structures of the adjuvant.
Pack SizePriceAvailabilityQuantity
1 mg$86In Stock
5 mg$219In Stock
10 mg$359In Stock
25 mg$583In Stock
50 mg$805In Stock
100 mg$1,080In Stock
200 mg$1,460In Stock
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Batch Information

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Purity:99.74%
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COA HNMR HPLC

Product Introduction

Bioactivity
Description
AXC-715 trihydrochloride (T785 trihydrochloride) is a TLR7/TLR8 dual agonist for the synthesis of antibody-adjuvanted immunocouplings. The couplings are mostly programmed death ligand 1 (PD-L1) attached to one or more antibody structures of the adjuvant.
SynonymsT785 trihydrochloride
Chemical Properties
Molecular Weight420.81
FormulaC18H28Cl3N5
Cas No.2479276-17-8
SmilesNC1=NC2=C(C=CC=C2)C3=C1N=C(CCCC)N3CCCCN.Cl.Cl.Cl
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 42.08 mg/mL (100 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.3764 mL11.8818 mL23.7637 mL118.8185 mL
5 mM0.4753 mL2.3764 mL4.7527 mL23.7637 mL
10 mM0.2376 mL1.1882 mL2.3764 mL11.8818 mL
20 mM0.1188 mL0.5941 mL1.1882 mL5.9409 mL
50 mM0.0475 mL0.2376 mL0.4753 mL2.3764 mL
100 mM0.0238 mL0.1188 mL0.2376 mL1.1882 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

TLR8TLR7T-785 TrihydrochlorideT785 TrihydrochlorideT-785T785T 785 TrihydrochlorideT 785AXC-715 TrihydrochlorideAXC715 TrihydrochlorideAXC-715AXC715AXC 715 TrihydrochlorideAXC 715
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