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Anti-MADCAM1 Antibody (8Q587)
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Catalog No. TMAH-00719
Alias MAdCAM-1, MADCAM1, MACAM1
Anti-MADCAM1 Antibody (8Q587) is an antibody targeting MADCAM1. Anti-MADCAM1 Antibody (8Q587) can be used in ELISA, FCM.
Anti-MADCAM1 Antibody (8Q587)
Anti-MADCAM1 Antibody (8Q587)
😃Good
Catalog No. TMAH-00719Alias MAdCAM-1, MADCAM1, MACAM1
Anti-MADCAM1 Antibody (8Q587) is an antibody targeting MADCAM1. Anti-MADCAM1 Antibody (8Q587) can be used in ELISA, FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $209 | 7-10 days | |
| 100 μL | $348 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Recombinant Rabbit Monoclonal Application: ELISA, FCM Reactivity: Human |
| Alias | MAdCAM-1, MADCAM1, MACAM1 |
| Ig Type | Rabbit IgG |
| Clone | 8Q587 |
| Reactivity | Human |
| Verified Activity | Overlay Peak curve showing PC3 cells surface stained with TMAH-00719 (red line) at 1:100. The cells were incubated in 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1ug/1*10^6 cells) for 45min at 4°C. The secondary antibody used was FITC-conjugated Goat Anti-rabbit IgG(H+L) at 1:200 dilution for 35min at 4°C.Control antibody (green line) was rabbit IgG (1ug/1*10^6 cells) used under the same conditions. Acquisition of >10,000 events was performed. |
| Application | ELISA, FCM |
| Recommended Dose | FCM:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Membrane; Single-pass type I membrane protein. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening, independent of L-selectin binding. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human MADCAM1 |
| Antigen Species | Human |
| Gene ID | 8174 |
| Uniprot ID | |
| Biology Area | Neuroscience, Cardiovascular, Immunology, Signal transduction |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Sci Citations
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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