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(R)-BI-2852

🥰Excellent
Catalog No. T72084Cas No. 2375482-49-6

(R)-BI-2852 can be used as (R)-5-isoindolin-1-one is used as an inhibitor of the RAS family of proteins and as a compound for the treatment and prevention of tumours. (R)-BI-2852 has Antiproliferative and antitumour agent activity.

(R)-BI-2852
Other Forms of (R)-BI-2852:
BI-2852T105332375482-51-0
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(R)-BI-2852

🥰Excellent
Purity: 97.78%
Catalog No. T72084Cas No. 2375482-49-6
(R)-BI-2852 can be used as (R)-5-isoindolin-1-one is used as an inhibitor of the RAS family of proteins and as a compound for the treatment and prevention of tumours. (R)-BI-2852 has Antiproliferative and antitumour agent activity.
Pack SizePriceAvailabilityQuantity
1 mg$85In Stock
5 mg$163In Stock
10 mg$257In Stock
25 mg$416In Stock
50 mgPreferentialIn Stock
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Bulk & Custom
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
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Batch Information

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Purity:97.78%
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COA HPLC HNMR

Product Introduction

Bioactivity
Description
(R)-BI-2852 can be used as (R)-5-isoindolin-1-one is used as an inhibitor of the RAS family of proteins and as a compound for the treatment and prevention of tumours. (R)-BI-2852 has Antiproliferative and antitumour agent activity.
Chemical Properties
Molecular Weight516.59
FormulaC31H28N6O2
Cas No.2375482-49-6
SmilesC(NCC=1C=C2N(CC3=CN(C)C=N3)C=CC2=CC1)C4=C(C=5C(N4)=CC=CC5)[C@H]6C=7C(C(=O)N6)=CC=C(O)C7
Relative Density.1.41 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (96.79 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.9358 mL9.6789 mL19.3577 mL96.7886 mL
5 mM0.3872 mL1.9358 mL3.8715 mL19.3577 mL
10 mM0.1936 mL0.9679 mL1.9358 mL9.6789 mL
20 mM0.0968 mL0.4839 mL0.9679 mL4.8394 mL
50 mM0.0387 mL0.1936 mL0.3872 mL1.9358 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

RasBI-2852BI2852BI 2852(R)5hydroxy3(2((((1((1methyl1Himidazol4yl)methyl)1Hindol6yl)methyl)amino)methyl)1Hindol3yl)isoindolin1one
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