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Anti-IFNAR1 Antibody (5I705) is an antibody targeting IFNAR1. Anti-IFNAR1 Antibody (5I705) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $208 | 7-10 days | |
100 μL | $348 | 7-10 days |
Description | Antibody Type: Recombinant Rabbit Monoclonal Application: ELISA Reactivity: Human |
Alias | IFRC, IFN-α-REC, IFN-α/β R1, IFN-R-1, IFNbR1, IFNBR, IFN-aR1, IFNAR1, IFNAR, IFN-alpha-REC, IFN-alpha/β R1, IFN-alpha/beta R1, IFN α/β R1, CRF2-1, AVP |
Ig Type | Rabbit IgG |
Clone | 5I705 |
Reactivity | Human |
Application | ELISA |
Antibody Type | Monoclonal |
Subcellular Localization | [Isoform 1]: Cell membrane; Single-pass type I membrane protein. Late endosome. Lysosome. |
Construction | Recombinant Antibody |
Purification | Affinity-chromatography |
Appearance | Liquid |
Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Research Background | Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves. Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway. |
Conjucates | Unconjugated |
Immunogen | A synthetic peptide: Human IFNAR1 |
Antigen Species | Human |
Gene ID | 3454 |
Uniprot ID | |
Biology Area | Immunology |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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