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trans-Aconitic acid

Name: trans-Aconitic acid
Brand: TargetMol
SKU: T4861
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T4861Cas No. 4023-65-8

Trans-Aconitic acid is normally present in normal human urine, and it has been suggested that is present in larger amounts with Reye's syndrome and organic aciduria. trans-Aconitic acid is a substrate of enzyme trans-aconitate 2-methyltransferase (EC 2.1.1.144). Trans-aconitate in the urine is a biomarker for the consumption of soy products.trans-Aconitic acid is an antimicrobial agent that blocks the transformation of Leishmania donovani amastigotes to prostigotes.

trans-Aconitic acid

🥰Excellent

Purity: 98.7%

Catalog No. T4861Cas No. 4023-65-8

Pack Size	Price	Availability
50 mg	$30	In Stock
100 mg	$40	In Stock
500 mg	$73	In Stock
1 g	$106	In Stock
2 g	$156	In Stock
1 mL x 10 mM (in DMSO)	$39	In Stock

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Batch Information

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Purity:98.7%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description

Targets&IC50

ATP citrate synthase:>1 mM(Ki,rat)

Chemical Properties

Molecular Weight	174.11
Formula	C₆H₆O₆
Cas No.	4023-65-8
Smiles	OC(=O)C\C(=C/C(O)=O)C(O)=O
Relative Density.	1.66g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (315.89 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.7435 mL	28.7175 mL	57.4350 mL	287.1748 mL
5 mM	1.1487 mL	5.7435 mL	11.4870 mL	57.4350 mL
10 mM	0.5743 mL	2.8717 mL	5.7435 mL	28.7175 mL
20 mM	0.2872 mL	1.4359 mL	2.8717 mL	14.3587 mL
50 mM	0.1149 mL	0.5743 mL	1.1487 mL	5.7435 mL
100 mM	0.0574 mL	0.2872 mL	0.5743 mL	2.8717 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc