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RG7713 (RO 5028442) has been used in trials studying Autistic Disorder.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $54 | In Stock | In Stock | |
| 5 mg | $121 | In Stock | In Stock | |
| 10 mg | $211 | In Stock | In Stock | |
| 25 mg | $356 | In Stock | In Stock | |
| 50 mg | $533 | In Stock | In Stock | |
| 100 mg | $769 | Backorder | Backorder |
| Description | RG7713 (RO 5028442) has been used in trials studying Autistic Disorder. |
| Targets&IC50 | V1a receptor (mouse):39nM(Ki), V1a receptor (human):1 nM(Ki) |
| In vitro | RO5028442 (compound 8) has excellent binding in and functional affinity for hV1a, moderate mouse affinity, and excellent selectivity versus human V2 (hV2) and human oxytocin (hOT) receptors. RO5028442 shows high solubility. RO5028442 is found to be highly selective against a panel of 89 targets. Finally, RO5028442 is identified as a suitable compound for clinical studies[1]. |
| Synonyms | RO 5028442 |
| Molecular Weight | 437.96 |
| Formula | C25H28ClN3O2 |
| Cas No. | 920022-47-5 |
| Smiles | CN(C)CCn1cc(C(=O)N2CCC3(CC2)OCc2ccccc32)c2ccc(Cl)cc12 |
| Relative Density. | 1.28 g/cm3 (Predicted) |
| Color | White |
| Appearance | solid |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||
| Solubility Information | DMSO: 4.38 mg/mL (10 mM), Sonication is recommended. | ||||||||||||||||||||
| In Vivo Formulation | 10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (2.28 mM), Sonication is recommended. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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