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Anti-CXCL1 Antibody (2Q668) (Synonyms: SCYB1, P450c21B, NAP-3, MGSA-a, MGSA, GROa, GRO1, CYP21B, CYP21||...)

Catalog No. TMAY-01275 Copy Product Info
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Anti-CXCL1 Antibody (2Q668) is a Rabbit antibody targeting CXCL1. Anti-CXCL1 Antibody (2Q668) can be used in ELISA.

Anti-CXCL1 Antibody (2Q668)

Copy Product Info
🥰Excellent
Catalog No. TMAY-01275
Synonyms SCYB1, P450c21B, NAP-3, MGSA-a, MGSA, GROa, GRO1, CYP21B, CYP21, CPS1, chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, α), chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha), CAH1, CA21H

Anti-CXCL1 Antibody (2Q668) is a Rabbit antibody targeting CXCL1. Anti-CXCL1 Antibody (2Q668) can be used in ELISA.

Anti-CXCL1 Antibody
(2Q668)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$2687-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-CXCL1 Antibody (2Q668) is a Rabbit antibody targeting CXCL1. Anti-CXCL1 Antibody (2Q668) can be used in ELISA.
SynonymsSCYB1, P450c21B, NAP-3, MGSA-a, MGSA, GROa, GRO1, CYP21B, CYP21, CPS1, chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, α), chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha), CAH1, CA21H
Ig Type
Rabbit IgG
Clone
2Q668
Reactivity
Human
Specificity
Human CXCL1
Application
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human CXCL1 (rh CXCL1; TMPY-02868; P09341-1; Ala35-Asn107).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundThe Chemokine (C-X-C motif) Ligand 1, CXCL1, is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GRO?, KC, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimulating activity, alpha (MSGA-a). CXCL1 already known to be important in osteoarthritis (OA), as a novel target gene of transcription factor AP-2? in chondrocytes and support the important role of AP-2? in cartilage. CXCL1 is a potent neutrophil chemoattractant with recognized roles in angiogenesis and inflammation. CXCL1 is a novel immediate PTH/PTHrP-responsive gene. CXCL1 may act as a chemoattractant for osteoclast precursors. CXCL1 may also have important pro-nociceptive effects via its direct actions on sensory neurons, and may induce long-term changes that involve protein synthesis. CXCL1 plays a critical nonredundant role in the development of experimental Lyme arthritis and carditis via CXCR2-mediated recruitment of neutrophils into the site of infection. CXCL1 functions through CXCR2 to transactivate the EGFR by proteolytic cleavage of HB-EGF, leading to activation of MAPK signalling and increased proliferation of epithelial ovarian cancer (EOC) cells. It might limit tumor growth by reinforcing senescence early in tumorigenesis. Thus, CXCL1 plays a role in spinal cord development by inhibiting the migration of oligodendrocyte precursors and is involved in the processes of angiogenesis, inflammation, wound healing, and tumorigenesis.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human CXCL1 Protein (TMPY-02868)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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