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Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Secretin (swine), a neuroendocrine hormone first identified as secreted by S cells in the duodenal mucosa, is a 27-amino acid peptide targeting secretin receptors. Present in all mature enteroendocrine cell subsets, it is stimulated by fatty acids and promotes pancreatic secretion of water and bicarbonate. Secretin has diverse effects on organ systems and is utilized in research on the digestive system, central nervous system, and energy metabolism [1] [2].
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Description | Secretin (swine), a neuroendocrine hormone first identified as secreted by S cells in the duodenal mucosa, is a 27-amino acid peptide targeting secretin receptors. Present in all mature enteroendocrine cell subsets, it is stimulated by fatty acids and promotes pancreatic secretion of water and bicarbonate. Secretin has diverse effects on organ systems and is utilized in research on the digestive system, central nervous system, and energy metabolism [1] [2]. |
In vitro | Secretin (swine) at concentrations of 10−7 M and 10−6 M, administered over periods ranging from 24 hours to 72 hours and up to 7 days, enhances biliary growth through engagement with secretin receptors (SR). Additionally, SR knockout diminishes biliary proliferation by attenuating cAMP-dependent signaling pathways [2]. |
In vivo | Secretin (swine) administered at 2.5 nM/kg body weight per day via osmotic minipumps for one week induces biliary cell proliferation in mice by modulating the levels of microRNA 125b and microRNA let7a [2]. |
Molecular Weight | 3055.41 |
Formula | C130H220N44O41 |
CAS No. | 17034-35-4 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Secretin (swine) 17034-35-4 inhibitor inhibit