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Anti-NAALADL1 Antibody (6J529) (Synonyms: N-acetylated α-linked acidic dipeptidase-like 1, N-acetylated alpha-l...)

Catalog No. TMAY-01698 Copy Product Info
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Anti-NAALADL1 Antibody (6J529) is a Mouse antibody targeting NAALADL1. Anti-NAALADL1 Antibody (6J529) can be used in ELISA.

Anti-NAALADL1 Antibody (6J529)

Copy Product Info
🥰Excellent
Catalog No. TMAY-01698
Synonyms N-acetylated α-linked acidic dipeptidase-like 1, N-acetylated alpha-linked acidic dipeptidase-like 1, Naaladasel, Gm964

Anti-NAALADL1 Antibody (6J529) is a Mouse antibody targeting NAALADL1. Anti-NAALADL1 Antibody (6J529) can be used in ELISA.

Anti-NAALADL1 Antibody
(6J529)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$1997-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-NAALADL1 Antibody (6J529) is a Mouse antibody targeting NAALADL1. Anti-NAALADL1 Antibody (6J529) can be used in ELISA.
SynonymsN-acetylated α-linked acidic dipeptidase-like 1, N-acetylated alpha-linked acidic dipeptidase-like 1, Naaladasel, Gm964
Ig Type
Mouse IgG2a
Clone
6J529
Reactivity
Human
Specificity
Human NAALADL1
Application
Recommended Dose
ELISA: 1:1000-1:2000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human NAALADL1 (rh NAALADL1; TMPY-01215; NP_005459.2; Pro 29-Leu 740). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundN-acetylated-alpha-linked acidic dipeptidase-like protein, also known as NAALADL1, NAALADase L, and Ileal dipeptidyl-peptidase, is a Single-pass type II membrane protein and a member of the peptidase M28 family and M28B subfamily. NAALADase L is mainly expressed in the distal small intestine. It is also expressed in the spleen and testis and Weakly expressed in the brain, locating mainly to the brain stem, amygdala, thalamus, and ventral striatum. NAALADase L is a chloride-activated, membrane-bound, metallopeptidase that cleaves the endogenous neuropeptide N-acetyl-aspartyl-glutamate (NAAG). NAAG acts as a partial NMDA agonist as well as a full agonist at the presynaptic metabotropic glutamate receptor 3 (mGluR3), where it acts to reduce glutamate release. NAALADase L also exhibits a dipeptidyl-peptidase IV type activity. NAALADase inhibition may be a novel therapeutic approach to reduce or inhibit heightened aggressiveness, and possibly to treat aggressive behavior associated with psychiatric disorders.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human NAALADL1 protein (TMPY-01215)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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