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Anti-NAALADL1 Antibody (6J529)
😃Good
Catalog No. TMAY-01698
Alias N-acetylated α-linked acidic dipeptidase-like 1, N-acetylated alpha-linked acidic dipeptidase-like 1, Naaladasel, Gm964
Anti-NAALADL1 Antibody (6J529) is a Mouse antibody targeting NAALADL1. Anti-NAALADL1 Antibody (6J529) can be used in ELISA.
Anti-NAALADL1 Antibody (6J529)
Anti-NAALADL1 Antibody (6J529)
😃Good
Catalog No. TMAY-01698Alias N-acetylated α-linked acidic dipeptidase-like 1, N-acetylated alpha-linked acidic dipeptidase-like 1, Naaladasel, Gm964
Anti-NAALADL1 Antibody (6J529) is a Mouse antibody targeting NAALADL1. Anti-NAALADL1 Antibody (6J529) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | 189 € | 7-10 days |
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Antigen Details
Chemical Properties
| Description | Anti-NAALADL1 Antibody (6J529) is a Mouse antibody targeting NAALADL1. Anti-NAALADL1 Antibody (6J529) can be used in ELISA. |
| Alias | N-acetylated α-linked acidic dipeptidase-like 1, N-acetylated alpha-linked acidic dipeptidase-like 1, Naaladasel, Gm964 |
| Ig Type | Monoclonal Mouse IgG2a |
| Clone | 6J529 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human NAALADL1 (rh NAALADL1; TMPY-01215; NP_005459.2; Pro 29-Leu 740). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | N-acetylated-alpha-linked acidic dipeptidase-like protein, also known as NAALADL1, NAALADase L, and Ileal dipeptidyl-peptidase, is a Single-pass type II membrane protein and a member of the peptidase M28 family and M28B subfamily. NAALADase L is mainly expressed in the distal small intestine. It is also expressed in the spleen and testis and Weakly expressed in the brain, locating mainly to the brain stem, amygdala, thalamus, and ventral striatum. NAALADase L is a chloride-activated, membrane-bound, metallopeptidase that cleaves the endogenous neuropeptide N-acetyl-aspartyl-glutamate (NAAG). NAAG acts as a partial NMDA agonist as well as a full agonist at the presynaptic metabotropic glutamate receptor 3 (mGluR3), where it acts to reduce glutamate release. NAALADase L also exhibits a dipeptidyl-peptidase IV type activity. NAALADase inhibition may be a novel therapeutic approach to reduce or inhibit heightened aggressiveness, and possibly to treat aggressive behavior associated with psychiatric disorders. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human NAALADL1 protein (TMPY-01215) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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