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SU5205

Name: SU5205
Brand: TargetMol
SKU: T3566
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T3566Cas No. 3476-86-6

Alias SU 5205

SU5205 is a VEGFR2 inhibitor.

SU5205

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Purity: 99.67%

Catalog No. T3566Alias SU 5205Cas No. 3476-86-6

SU5205 is a VEGFR2 inhibitor.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
25 mg	$29	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.67%

Color:White to Yellow

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COA

Product Introduction

SU5205 AI Summary

SU5205 shows bioactivities such as inducing NQO1 activity in mouse Hepa-1c1c7 cells, evidenced by the required drug level to double basal enzyme activity after 48 hours, and exhibiting cytotoxicity against these cells. Additionally, it induces both NQO1 and CYP1A1 activities at a concentration of 20 μM after 48 hours, with a noted ratio of CYP1 induction to NQO1 induction in the same cells..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	SU5205 is a VEGFR2 inhibitor.
Targets&IC50	FLK1:9.6 μM (IC50)
Synonyms	SU 5205

Chemical Properties

Molecular Weight	239.24
Formula	C₁₅H₁₀FNO
Cas No.	3476-86-6
Smiles	Fc1ccc(C=C2C(=O)Nc3ccccc23)cc1
Relative Density.	1.306 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (209 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.1799 mL	20.8995 mL	41.7990 mL	208.9952 mL
5 mM	0.8360 mL	4.1799 mL	8.3598 mL	41.7990 mL
10 mM	0.4180 mL	2.0900 mL	4.1799 mL	20.8995 mL
20 mM	0.2090 mL	1.0450 mL	2.0900 mL	10.4498 mL
50 mM	0.0836 mL	0.4180 mL	0.8360 mL	4.1799 mL
100 mM	0.0418 mL	0.2090 mL	0.4180 mL	2.0900 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc