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Human α-Defensin 6

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Catalog No. T80362

Human α-Defensin 6, a 32-residue, cysteine-rich peptide, plays a crucial role in mucosal immunity by inhibiting bacterial invasion through the formation of ordered self-assembly fibrils and nanonets, which bind to bacterial surface proteins and entangle the bacteria. Additionally, Human α-Defensin 6 impedes biofilm formation by C. albicans [1] [2].

Human α-Defensin 6

Human α-Defensin 6

😃Good
Catalog No. T80362
Human α-Defensin 6, a 32-residue, cysteine-rich peptide, plays a crucial role in mucosal immunity by inhibiting bacterial invasion through the formation of ordered self-assembly fibrils and nanonets, which bind to bacterial surface proteins and entangle the bacteria. Additionally, Human α-Defensin 6 impedes biofilm formation by C. albicans [1] [2].
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Product Introduction

Bioactivity
Description
Human α-Defensin 6, a 32-residue, cysteine-rich peptide, plays a crucial role in mucosal immunity by inhibiting bacterial invasion through the formation of ordered self-assembly fibrils and nanonets, which bind to bacterial surface proteins and entangle the bacteria. Additionally, Human α-Defensin 6 impedes biofilm formation by C. albicans [1] [2].
Chemical Properties
Molecular Weight3708.22
FormulaC156H228N46O46S7
SequenceAla-Phe-Thr-Cys-His-Cys-Arg-Arg-Ser-Cys-Tyr-Ser-Thr-Glu-Tyr-Ser-Tyr-Gly-Thr-Cys-Thr-Val-Met-Gly-Ile-Asn-His-Arg-Phe-Cys-Cys-Leu (Disulfide bridge: Cys4-Cys31, Cys6-Cys20, Cys10-Cys30)
Sequence ShortAFTCHCRRSCYSTEYSYGTCTVMGINHRFCCL (Disulfide bridge: Cys4-Cys31, Cys6-Cys20, Cys10-Cys30)
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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