Shopping Cart

Remove All
Your shopping cart is currently empty

HIF1-IN-3

Name: HIF1-IN-3
Brand: TargetMol
SKU: T9890
Price: 38 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T9890Cas No. 333314-79-7

Alias Benzenepropanamide, N-[(8-hydroxy-7-quinolinyl)(4-methoxyphenyl)methyl]-

HIF1-IN-3 (Benzenepropanamide, N-[(8-hydroxy-7-quinolinyl)(4-methoxyphenyl)methyl]-) is an effective inhibitor of HIF-1 (EC50 = 0.9 μM) and can be used in anticancer studies.

HIF1-IN-3

🥰Excellent

Purity: 99.59%

Catalog No. T9890Alias Benzenepropanamide, N-[(8-hydroxy-7-quinolinyl)(4-methoxyphenyl)methyl]-Cas No. 333314-79-7

HIF1-IN-3 (Benzenepropanamide, N-[(8-hydroxy-7-quinolinyl)(4-methoxyphenyl)methyl]-) is an effective inhibitor of HIF-1 (EC50 = 0.9 μM) and can be used in anticancer studies.

Pack Size	Price	Availability
5 mg	$38	In Stock
10 mg	$58	In Stock
25 mg	$118	In Stock
50 mg	$223	In Stock
100 mg	$307	In Stock
200 mg	$445	In Stock
1 mL x 10 mM (in DMSO)	$48	In Stock

Add to Cart

Add to Quotation

Bulk & Custom

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:99.59%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	HIF1-IN-3 (Benzenepropanamide, N-[(8-hydroxy-7-quinolinyl)(4-methoxyphenyl)methyl]-) is an effective inhibitor of HIF-1 (EC50 = 0.9 μM) and can be used in anticancer studies.
Targets&IC50	HIF1:0.9 μM (EC50)
Synonyms	Benzenepropanamide, N-[(8-hydroxy-7-quinolinyl)(4-methoxyphenyl)methyl]-

Chemical Properties

Molecular Weight	412.48
Formula	C₂₆H₂₄N₂O₃
Cas No.	333314-79-7
Smiles	COc1ccc(cc1)C(NC(=O)CCc1ccccc1)c1ccc2cccnc2c1O
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 245 mg/mL (593.97 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4244 mL	12.1218 mL	24.2436 mL	121.2180 mL
5 mM	0.4849 mL	2.4244 mL	4.8487 mL	24.2436 mL
10 mM	0.2424 mL	1.2122 mL	2.4244 mL	12.1218 mL
20 mM	0.1212 mL	0.6061 mL	1.2122 mL	6.0609 mL
50 mM	0.0485 mL	0.2424 mL	0.4849 mL	2.4244 mL
100 mM	0.0242 mL	0.1212 mL	0.2424 mL	1.2122 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc