Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Lesogaberan (AZD-3355) hydrochloride is a potent and selective GABA B receptor agonist with an EC 50 of 8.6 nM for human recombinant GABA B receptor. The affinity ( K i s) of Lesogaberan hydrochloride for rat GABA B and GABA A receptors, as measured by displacement of GABA binding in brain membranes: 5.1 nM and 1.4 μM, respectively. Lesogaberan hydrochloride inhibits transient lower esophageal sphincter relaxation through a peripheral mode of action .
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | Inquiry | $ 332.00 | |
50 mg | Inquiry | $ 1,690.00 | |
100 mg | Inquiry | $ 2,500.00 |
Description | Lesogaberan (AZD-3355) hydrochloride is a potent and selective GABA B receptor agonist with an EC 50 of 8.6 nM for human recombinant GABA B receptor. The affinity ( K i s) of Lesogaberan hydrochloride for rat GABA B and GABA A receptors, as measured by displacement of GABA binding in brain membranes: 5.1 nM and 1.4 μM, respectively. Lesogaberan hydrochloride inhibits transient lower esophageal sphincter relaxation through a peripheral mode of action . |
Synonyms | AZD-3355 hydrochloride |
Molecular Weight | 177.54 |
Formula | C3H10ClFNO2P |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Lesogaberan hydrochloride AZD3355 Hydrochloride Lesogaberan Hydrochloride AZD-3355 Hydrochloride AZD 3355 Hydrochloride AZD-3355 hydrochloride inhibitor inhibit