Powder: -20°C for 3 years | In solvent: -80°C for 1 year
VRT-534 is a compound that selectively targets connexin 26 (Cx26), demonstrating dose-responsive binding to both wild-type (WT) Cx26 and the mutant Cx26 K188N, with EC50 values of 19 μM and 5 μM, respectively. It has potential applications in research concerning hearing impairment [1].
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Description | VRT-534 is a compound that selectively targets connexin 26 (Cx26), demonstrating dose-responsive binding to both wild-type (WT) Cx26 and the mutant Cx26 K188N, with EC50 values of 19 μM and 5 μM, respectively. It has potential applications in research concerning hearing impairment [1]. |
In vitro | VRT-534 (Compound 3) at a concentration of 50 nM and after 24 hours of treatment can restore the vitality of HeLa cells [1]. |
Molecular Weight | 497.99 |
Formula | C25H24ClN3O4S |
CAS No. | 926664-32-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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VRT-534 926664-32-6 inhibitor inhibit