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ISOGINKGETIN

🥰Excellent
Catalog No. T4S21320Cas No. 548-19-6
Alias 4',4'''-Dimethylamentoflavone

1. ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion with potency comparable to that of rosiglitazone, a known modulator of adiponectin production. 2. Isoginkgetin has anti-tumor activity, the mechanistic basis is splicing inhibition , thus, pre-mRNA splicing inhibitors may represent a novel avenue for development of new anti-cancer agents.3. Isoginkgetin can inhibit tumor cell invasion by regulating phosphatidylinositol 3-kinase/Akt-dependent matrix metalloproteinase-9 expression. 4. Isoginkgetin (0.3mg/kg ip for 3d) can reduce the level of O2·- in plasma and erythroeyte and sometimes increase the activity of SOD in anoxic rats, the action being stronger than aspirin.

ISOGINKGETIN

ISOGINKGETIN

🥰Excellent
Purity: 99.72%
Catalog No. T4S21320Alias 4',4'''-DimethylamentoflavoneCas No. 548-19-6
1. ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion with potency comparable to that of rosiglitazone, a known modulator of adiponectin production. 2. Isoginkgetin has anti-tumor activity, the mechanistic basis is splicing inhibition , thus, pre-mRNA splicing inhibitors may represent a novel avenue for development of new anti-cancer agents.3. Isoginkgetin can inhibit tumor cell invasion by regulating phosphatidylinositol 3-kinase/Akt-dependent matrix metalloproteinase-9 expression. 4. Isoginkgetin (0.3mg/kg ip for 3d) can reduce the level of O2·- in plasma and erythroeyte and sometimes increase the activity of SOD in anoxic rats, the action being stronger than aspirin.
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Purity:99.72%
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Product Introduction

Bioactivity
Description
1. ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion with potency comparable to that of rosiglitazone, a known modulator of adiponectin production. 2. Isoginkgetin has anti-tumor activity, the mechanistic basis is splicing inhibition , thus, pre-mRNA splicing inhibitors may represent a novel avenue for development of new anti-cancer agents.3. Isoginkgetin can inhibit tumor cell invasion by regulating phosphatidylinositol 3-kinase/Akt-dependent matrix metalloproteinase-9 expression. 4. Isoginkgetin (0.3mg/kg ip for 3d) can reduce the level of O2·- in plasma and erythroeyte and sometimes increase the activity of SOD in anoxic rats, the action being stronger than aspirin.
Alias4',4'''-Dimethylamentoflavone
Chemical Properties
Molecular Weight566.51
FormulaC32H22O10
Cas No.548-19-6
SmilesCOc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(-c3cc(ccc3OC)-c3cc(=O)c4c(O)cc(O)cc4o3)c2o1
Relative Density.1.506g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 83.3 mg/mL (147.04 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.7652 mL8.8260 mL17.6519 mL88.2597 mL
5 mM0.3530 mL1.7652 mL3.5304 mL17.6519 mL
10 mM0.1765 mL0.8826 mL1.7652 mL8.8260 mL
20 mM0.0883 mL0.4413 mL0.8826 mL4.4130 mL
50 mM0.0353 mL0.1765 mL0.3530 mL1.7652 mL
100 mM0.0177 mL0.0883 mL0.1765 mL0.8826 mL

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