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BD-1047 dihydrobromide

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Catalog No. T1740Cas No. 138356-21-5
Alias BD1047.2HBr

BD-1047 dihydrobromide (BD1047.2HBr) , a selective functional antagonist of sigma receptors, has antipsychotic activity in animal models predictive of efficacy in schizophrenia.

BD-1047 dihydrobromide
Other Forms of BD-1047 dihydrobromide:
BD-1047T205677138356-20-4
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BD-1047 dihydrobromide

🥰Excellent
Purity: 99.39%
Catalog No. T1740Alias BD1047.2HBrCas No. 138356-21-5
BD-1047 dihydrobromide (BD1047.2HBr) , a selective functional antagonist of sigma receptors, has antipsychotic activity in animal models predictive of efficacy in schizophrenia.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$31In StockIn Stock
2 mg$41In StockIn Stock
5 mg$67In StockIn Stock
10 mg$87In StockIn Stock
25 mg$171In StockIn Stock
50 mg$306In StockIn Stock
100 mg$516In StockIn Stock
1 mL x 10 mM (in DMSO)$68In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.39%
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Product Introduction

Bioactivity
Description
BD-1047 dihydrobromide (BD1047.2HBr) , a selective functional antagonist of sigma receptors, has antipsychotic activity in animal models predictive of efficacy in schizophrenia.
SynonymsBD1047.2HBr
Chemical Properties
Molecular Weight437.04
FormulaC13H22Br2Cl2N2
Cas No.138356-21-5
SmilesBr.Br.CN(C)CCN(C)CCc1ccc(Cl)c(Cl)c1
Relative Density.no data available
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (114.41 mM), Sonication is recommended.
H2O: 43.7 mg/mL (100 mM), Sonication and heating are recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (4.58 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM2.2881 mL11.4406 mL22.8812 mL114.4060 mL
5 mM0.4576 mL2.2881 mL4.5762 mL22.8812 mL
10 mM0.2288 mL1.1441 mL2.2881 mL11.4406 mL
20 mM0.1144 mL0.5720 mL1.1441 mL5.7203 mL
50 mM0.0458 mL0.2288 mL0.4576 mL2.2881 mL
100 mM0.0229 mL0.1144 mL0.2288 mL1.1441 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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