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15(S)-HETrE

Name: 15(S)-HETrE
Brand: TargetMol
SKU: T37400
Rating: 4.5 (1 reviews)

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Catalog No. T37400Cas No. 92693-02-2

15(S)-HETrE is the hydroxy-trienoic acid resulting from 15-lipoxygenation of dihomo-γ-linolenic acid. It inhibits 5-LO in human PMNL with an IC50 value of 4.6 μM. In RBL cells, 15(S)-HETrE also inhibits 5-LO, but is approximately 1/20 as potent as 15(S)-HpETE.

15(S)-HETrE

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Catalog No. T37400Cas No. 92693-02-2

Pack Size	Price	USA Warehouse	Global Warehouse
25 μg	$287	35 days	35 days
50 μg	$543	35 days	35 days
100 μg	$993	35 days	35 days
500 μg	$2,230	35 days	35 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	322.48
Formula	C₂₀H₃₄O₃
Cas No.	92693-02-2
Smiles	C(=C/C=C\C/C=C\CCCCCCC(O)=O)\[C@H](CCCCC)O

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

0.1 M Na2CO3: 2 mg/mL (6.2 mM), Sonication is recommended.

Ethanol: Miscible

DMF: Miscible

PBS (pH 7.2): 0.8 mg/mL (2.48 mM), Sonication is recommended.

DMSO: Miscible

Solution Preparation Table

PBS (pH 7.2)/0.1 M Na2CO3

	1mg	5mg	10mg	50mg
1 mM	3.1010 mL	15.5048 mL	31.0097 mL	155.0484 mL

0.1 M Na2CO3

	1mg	5mg	10mg	50mg
5 mM	0.6202 mL	3.1010 mL	6.2019 mL	31.0097 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc