Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CVN636, a potent and selective allosteric agonist for the mGluR7 receptor, exhibits oral activity and CNS permeability [1], with an EC50 of 7 nM for human mGluR7.
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Description | CVN636, a potent and selective allosteric agonist for the mGluR7 receptor, exhibits oral activity and CNS permeability [1], with an EC50 of 7 nM for human mGluR7. |
Targets&IC50 | mGluR7 (human):7 nM (EC 50 ) |
In vivo | CVN636, administered orally at doses ranging from 0.3 to 3 mg/kg, reduces ethanol self-administration in msP rats [1]. |
Molecular Weight | 377.43 |
Formula | C19H20FNO4S |
CAS No. | 2226732-62-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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CVN636 2226732-62-1 inhibitor inhibit