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H-γ-Glu-Gln-OH (Synonyms: γ-Glutamylglutamine, γ-Glu-Gln)

Name: H-γ-Glu-Gln-OH
Brand: TargetMol
SKU: T78465
Price: 45 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. T78465 Copy Product Info

Purity: 99.84%

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H-γ-Glu-Gln-OH (γ-L-glutamyl-L-glutamine) is a highly hydrophilic dipeptide utilized as a building block for advanced drug delivery systems. Carriers composed of H-γ-Glu-Gln-OH, such as poly(L-γ-glutamylglutamine) (PGG), are characterized by high water solubility, superior drug-loading capacity, excellent biocompatibility, and low systemic toxicity. Conjugating drugs (e.g., Paclitaxel) to this peptide moiety significantly improves the solubility of hydrophobic agents and enhances tumor-targeting and tissue penetration (especially in glioblastoma models), leading to optimized anti-tumor efficacy.

H-γ-Glu-Gln-OH

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Catalog No. T78465

Synonyms γ-Glutamylglutamine, γ-Glu-Gln

Cas No. 10148-81-9

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Pack Size	Price	USA Stock	Global Stock
1 mg	$45	-	In Stock
5 mg	$106	-	In Stock
10 mg	$172	-	In Stock
25 mg	$288	-	In Stock
50 mg	$432	-	In Stock
100 mg	$626	-	In Stock
1 mL x 10 mM (in DMSO)	$117	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:99.84%

Appearance:Solid

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description

Synonyms

γ-Glutamylglutamine, γ-Glu-Gln

Chemical Properties

Molecular Weight	275.26
Formula	C₁₀H₁₇N₃O₆
Cas No.	10148-81-9
Smiles	[C@H](NC(CC[C@@H](C(O)=O)N)=O)(CCC(N)=O)C(O)=O
Sequence	γ-Glu-Gln
Sequence Short	γ-EQ

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (290.63 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.6329 mL	18.1646 mL	36.3293 mL	181.6464 mL
5 mM	0.7266 mL	3.6329 mL	7.2659 mL	36.3293 mL
10 mM	0.3633 mL	1.8165 mL	3.6329 mL	18.1646 mL
20 mM	0.1816 mL	0.9082 mL	1.8165 mL	9.0823 mL
50 mM	0.0727 mL	0.3633 mL	0.7266 mL	3.6329 mL
100 mM	0.0363 mL	0.1816 mL	0.3633 mL	1.8165 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

Citations

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

r-Glutamylglutaminer-Glu-GlnH-r-Glu-Gln-OHH-gamma-Glu-Gln-OHgamma-Glutamylglutaminegamma-Glu-Gln