Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty

Dargistotug

😃Good
Catalog No. T82609Cas No. 2649362-29-6
Alias M-6223, M6223

Dargistotug (M-6223), a fully human IgG1 monoclonal antibody, specifically binds to TIGIT (T cell immune receptor with Ig domain and ITIM), an inhibitory checkpoint receptor that plays a critical role in immune regulation. Dargistotug (M-6223) mitigates NK cell depletion, enhances cytokine secretion, modulates effector T cell activity, and increases regulatory T cell (Treg) function, thereby contributing to the broader immunosuppressive environment. Dargistotug (M-6223) has thus become an important agent in research focused on immune checkpoint inhibition.

Dargistotug

Dargistotug

😃Good
Purity: 95%
Catalog No. T82609Alias M-6223, M6223Cas No. 2649362-29-6
Dargistotug (M-6223), a fully human IgG1 monoclonal antibody, specifically binds to TIGIT (T cell immune receptor with Ig domain and ITIM), an inhibitory checkpoint receptor that plays a critical role in immune regulation. Dargistotug (M-6223) mitigates NK cell depletion, enhances cytokine secretion, modulates effector T cell activity, and increases regulatory T cell (Treg) function, thereby contributing to the broader immunosuppressive environment. Dargistotug (M-6223) has thus become an important agent in research focused on immune checkpoint inhibition.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$198-In Stock
5 mg$578-In Stock
10 mg$953-In Stock
25 mg$1,390-In Stock
50 mg$1,880-In Stock
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
TargetMol
View More

Batch Information

Select Batch
Purity:98.5% (SDS-PAGE); 97.2% (SEC-HPLC)
Contact us for more batch information

Product Introduction

Bioactivity
Description
Dargistotug (M-6223), a fully human IgG1 monoclonal antibody, specifically binds to TIGIT (T cell immune receptor with Ig domain and ITIM), an inhibitory checkpoint receptor that plays a critical role in immune regulation. Dargistotug (M-6223) mitigates NK cell depletion, enhances cytokine secretion, modulates effector T cell activity, and increases regulatory T cell (Treg) function, thereby contributing to the broader immunosuppressive environment. Dargistotug (M-6223) has thus become an important agent in research focused on immune checkpoint inhibition.
SynonymsM-6223, M6223
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetTIGIT/VSIG9/VSTM3
Chemical Properties
Molecular Weight144.70 kDa
Cas No.2649362-29-6
ColorTransparent
AppearanceLiquid
Antibody Information
IsotypeHuman IgG1 kappa
Recommended Isotype Control
Storage & Solubility Information
Storagestore at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature.

Calculator

  • Dilution Calculator
  • Reconstitution Calculator

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy Dargistotug | purchase Dargistotug | Dargistotug cost | order Dargistotug | Dargistotug molecular weight