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12-Ketodeoxycholic acid

Name: 12-Ketodeoxycholic acid
Brand: TargetMol
SKU: T14002
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T14002Cas No. 5130-29-0

12-Ketodeoxycholic acid, a bile acid and kidney metabolite, serves as a detectable marker for kidney injury [1].

12-Ketodeoxycholic acid

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Purity: 99.93%

Catalog No. T14002Cas No. 5130-29-0

12-Ketodeoxycholic acid, a bile acid and kidney metabolite, serves as a detectable marker for kidney injury [1].

Pack Size	Price	Availability
2 mg	$30	In Stock
5 mg	$46	In Stock
10 mg	$68	In Stock
25 mg	$123	In Stock
50 mg	$196	In Stock
100 mg	$287	In Stock
200 mg	$425	In Stock
1 mL x 10 mM (in DMSO)	$50	In Stock

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Batch Information

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Purity:99.93%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	12-Ketodeoxycholic acid, a bile acid and kidney metabolite, serves as a detectable marker for kidney injury [1].
In vitro	Bile acids, resulting from the conjugation of cholesterol, are synthesized by the liver and subsequently secreted into the intestine[1] for incorporation into bile.

Chemical Properties

Molecular Weight	390.56
Formula	C₂₄H₃₈O₄
Cas No.	5130-29-0
Smiles	C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3CCC4C[C@H](O)CC[C@]4(C)[C@H]3CC(=O)[C@]12C
Relative Density.	1.124 g/cm3 (Predicted)

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (256.04 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.5604 mL	12.8021 mL	25.6043 mL	128.0213 mL
5 mM	0.5121 mL	2.5604 mL	5.1209 mL	25.6043 mL
10 mM	0.2560 mL	1.2802 mL	2.5604 mL	12.8021 mL
20 mM	0.1280 mL	0.6401 mL	1.2802 mL	6.4011 mL
50 mM	0.0512 mL	0.2560 mL	0.5121 mL	2.5604 mL
100 mM	0.0256 mL	0.1280 mL	0.2560 mL	1.2802 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc