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DiOC5(3) is a lipophilic and membrane potential-sensitive fluorescent dye commonly used for staining mitochondria in live cells. DiOC5(3) can also selectively label leukaemia stem cells (LSCs) and inhibit proliferation, leading to excessive ROS production and inhibition of NF-κB nuclear translocation.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 2 mg | $30 | - | In Stock | |
| 5 mg | $48 | - | In Stock | |
| 10 mg | $68 | - | In Stock | |
| 25 mg | $143 | - | In Stock | |
| 50 mg | $228 | - | In Stock | |
| 100 mg | $378 | - | In Stock | |
| 200 mg | $559 | - | In Stock |
| Description | DiOC5(3) is a lipophilic and membrane potential-sensitive fluorescent dye commonly used for staining mitochondria in live cells. DiOC5(3) can also selectively label leukaemia stem cells (LSCs) and inhibit proliferation, leading to excessive ROS production and inhibition of NF-κB nuclear translocation. |
| Synonyms | 3,3'-Dipentyloxacarbocyanine iodide |
| Molecular Weight | 544.47 |
| Formula | C27H33IN2O2 |
| Cas No. | 53213-81-3 |
| Smiles | [I-].O1C=2C=CC=CC2N(C1=CC=CC=3OC=4C=CC=CC4[N+]3CCCCC)CCCCC |
| Storage | keep away from direct sunlight | store at -20°C | Shipping with blue ice. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 40 mg/mL (73.47 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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