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LX-2931

Name: LX-2931
Brand: TargetMol
SKU: T27864
Price: 258 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T27864Cas No. 948840-25-3

Alias LX-3305, LX3305, LX2931, LX 3305, LX 2931, ACB20034

LX-2931(LX-3305) is a sphingosine-1-phosphate cleavage enzyme (S1P) inhibitor for the treatment of rheumatoid arthritis.

LX-2931

🥰Excellent

Purity: 99.83%

Catalog No. T27864Alias LX-3305, LX3305, LX2931, LX 3305, LX 2931, ACB20034Cas No. 948840-25-3

LX-2931(LX-3305) is a sphingosine-1-phosphate cleavage enzyme (S1P) inhibitor for the treatment of rheumatoid arthritis.

Pack Size	Price	Availability
1 mg	$258	In Stock
5 mg	$642	In Stock
10 mg	$913	In Stock
25 mg	$1,370	In Stock
50 mg	$1,850	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.83%

ee:100%

Resource Download

COA CSFC HNMR LCMS

Product Introduction

Bioactivity

Description	LX-2931(LX-3305) is a sphingosine-1-phosphate cleavage enzyme (S1P) inhibitor for the treatment of rheumatoid arthritis.
Synonyms	LX-3305, LX3305, LX2931, LX 3305, LX 2931, ACB20034

Chemical Properties

Molecular Weight	245.23
Formula	C₉H₁₅N₃O₅
Cas No.	948840-25-3
Smiles	[C@@H]([C@@H]([C@@H](CO)O)O)(O)C=1NC(\C(=N\O)\C)=NC1
Relative Density.	1.31g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (407 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.0778 mL	20.3890 mL	40.7780 mL	203.8902 mL
5 mM	0.8156 mL	4.0778 mL	8.1556 mL	40.7780 mL
10 mM	0.4078 mL	2.0389 mL	4.0778 mL	20.3890 mL
20 mM	0.2039 mL	1.0195 mL	2.0389 mL	10.1945 mL
50 mM	0.0816 mL	0.4078 mL	0.8156 mL	4.0778 mL
100 mM	0.0408 mL	0.2039 mL	0.4078 mL	2.0389 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc